| Name | MNI 137 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5084 |
| Prices | $185.00, $755.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Modulator |
| Cas Number | 946619-21-2 |
| Chemical Name | 4-(8-Bromo-2,3-dihydro-2-oxo-1H-1,5-benzodiazepin-4-yl)-2-pyridinecarbonitrile |
| Formula | C15H9BrN4O |
| Molecular Weight | 341.16 |
| Purity | >98 % |
| Description | Selective negative allosteric modulator of group II mGlu receptors (IC 50 values are 8.3 and 12.6 nM for human and rat mGlu 2 inhibition of glutamate-induced calcium mobilization). Displays no activity at mGlu 1 , mGlu 4 , mGlu 5 or mGlu 8 receptors in a calcium mobilization assay. |
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