MNI-caged-L-glutamate

• Supplier: Tocris Bioscience
• Catalog: 2224
• Prices: $205.00, $845.00
• Sizes: 10 mg, 50 mg
• Cas Number: 295325-62-1
• Chemical Name: (S)-α-Amino-2,3-dihydro-4-methoxy-7-nitro-δ-oxo-1H-indole-1-pentanoicacid
• Formula: C14H17N3O6
• Molecular Weight: 323.3
• Purity: >98 %
• Description: MNI-caged glutamate that rapidly and efficiently releases glutamate (Cat. No. 0218) when photolysed (300 - 380 nm excitation). Water-soluble, highly resistant to hydrolysis, stable at neutral pH, and pharmacologically inactive at neuronal glutamate receptors (up to mM concentrations). 2.5-fold more efficient at releasing L-glutamate than NI-caged L-glutamate.

Product References

Photochemical and pharmacological evaluation of 7-nitroindolinyl-and - Photochemical and pharmacological evaluation of 7-nitroindolinyl-and

Canepari M, Nelson L, Papageorgiou G, Corrie JE, Ogden D. J Neurosci Methods. 2001 Nov 15;112(1):29-42.

Dendritic spine geometry is critical for AMPA receptor expression in hippocampal - Dendritic spine geometry is critical for AMPA receptor expression in hippocampal

Matsuzaki M, Ellis-Davies GC, Nemoto T, Miyashita Y, Iino M, Kasai H. Nat Neurosci. 2001 Nov;4(11):1086-92.

Comparative analysis of inhibitory effects of caged ligands for the NMDA - Comparative analysis of inhibitory effects of caged ligands for the NMDA

Maier W, Corrie JE, Papageorgiou G, Laube B, Grewer C. J Neurosci Methods. 2005 Mar 15;142(1):1-9.

New caged neurotransmitter analogs selective for glutamate receptor sub-types - New caged neurotransmitter analogs selective for glutamate receptor sub-types

Palma-Cerda F, Auger C, Crawford DJ, Hodgson AC, Reynolds SJ, Cowell JK, Swift KA, Cais O, Vyklicky L, Corrie JE, Ogden D. Neuropharmacology. 2012 Sep;63(4):624-34.