MNS

• Supplier: Tocris Bioscience
• Catalog: 2492
• Prices: $95.00
• Sizes: 50 mg
• Function Type: Inhibitor
• Cas Number: 1485-00-3
• Chemical Name: 3,4-Methylenedioxy-β-nitrostyrene
• Formula: C9H7NO4
• Molecular Weight: 193.16
• Purity: >99 %
• Description: Selective inhibitor of Src and Syk tyrosine kinases. Displays antiaggregative activity via inhibition of GPIIb/IIIa activation (IC 50 = 12.7 μ M for thrombin-induced platelet aggregation). Exhibits no effects on Ca 2+ -dependent enzymes, PKC or arachidonic acid metabolism.

Product References

Prevention of platelet glycoprotein IIb/IIIa activation by - Prevention of platelet glycoprotein IIb/IIIa activation by

Wang WY, Wu YC, Wu CC. Mol Pharmacol. 2006 Oct;70(4):1380-9. Epub 2006 Jul 12.

Synthesis and pharmacological evaluation of novel beta-nitrostyrene derivatives - Synthesis and pharmacological evaluation of novel beta-nitrostyrene derivatives

Wang WY, Hsieh PW, Wu YC, Wu CC. Biochem Pharmacol. 2007 Aug 15;74(4):601-11. Epub 2007 Jun 3.