Modafinil

• Supplier: Tocris Bioscience
• Catalog: 4395
• Prices: $89.00, $345.00
• Sizes: 10 mg, 50 mg
• Cas Number: 68693-11-8
• Chemical Name: 2-[(Diphenylmethyl)sulfinyl]acetamide
• Formula: C15H15NO2S
• Molecular Weight: 273.35
• Purity: >98 %
• Description: Psychostimulant that displays neuroprotective and antiparkinsonian activity in a primate model of Parkinson's disease. Promotes vigilence and wakefulness without the central and peripheral side effects associated with conventional dopaminergic psychostimulants. Mechanism of action is not fully understood, possibly via modulation of catecholamine/GABAergic neurotransmission.

Product References

Modafinil: an antinarcoleptic drug with a different neurochemical profile to - Modafinil: an antinarcoleptic drug with a different neurochemical profile to

Ferraro L, Antonelli T, O'Connor WT, Tanganelli S, Rambert FA, Fuxe K. Biol Psychiatry. 1997 Dec 15;42(12):1181-3.

Antiparkinsonian and neuroprotective effects of modafinil in the mptp-treated - Antiparkinsonian and neuroprotective effects of modafinil in the mptp-treated

Jenner P, Zeng BY, Smith LA, Pearce RK, Tel B, Chancharme L, Moachon G. Exp Brain Res. 2000 Jul;133(2):178-88.

Modafinil occupies dopamine and norepinephrine transporters in vivo and modulates - Modafinil occupies dopamine and norepinephrine transporters in vivo and modulates

Madras BK, Xie Z, Lin Z, Jassen A, Panas H, Lynch L, Johnson R, Livni E, Spencer TJ, Bonab AA, Miller GM, Fischman AJ. J Pharmacol Exp Ther. 2006 Nov;319(2):561-9. Epub 2006 Aug 2.