Monensin sodium salt

Name Monensin sodium salt
Supplier Tocris Bioscience
Catalog 1305
Prices $45.00
Sizes 500 mg
Cas Number 22373-78-0
Chemical Name 2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β-methoxy-α,γ,2,8-tetramethyl-1,6-Dioxaspiro[4.5]decane-7-butyricacidsodiumsalt
Formula C36H61NaO11
Molecular Weight 692.85
Description Sodium ionophore. Neutralizes acidic intracellular compartments. Disrupts Golgi apparatus structure and inhibits vesicular transport in eukaryotic cells. Induces apoptosis in prostate cancer cells. Antiprotozoal, antibacterial and antifungal agent.
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Product References

Alteration of intracellular traffic by monensin; mechanism, specificity and - Alteration of intracellular traffic by monensin; mechanism, specificity and

Mollenhauer HH, Morre DJ, Rowe LD. Biochim Biophys Acta. 1990 May 7;1031(2):225-46.

Monensin is a potent inducer of oxidative stress and inhibitor of androgen - Monensin is a potent inducer of oxidative stress and inhibitor of androgen

Ketola K, Vainio P, Fey V, Kallioniemi O, Iljin K. Mol Cancer Ther. 2010 Dec;9(12):3175-85.

Structure and antimicrobial properties of monensin A and its derivatives: summary - Structure and antimicrobial properties of monensin A and its derivatives: summary

Aowicki D, Huczynski A. Biomed Res Int. 2013;2013:742149.