Moxonidine hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 2264
• Prices: $139.00, $585.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 75536-04-8
• Chemical Name: 4-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinaminehydrochloride
• Formula: C9H12ClN5O.HCl
• Molecular Weight: 278.14
• Purity: >98 %
• Description: Mixed I 1 imidazoline receptor and α 2 -adrenergic agonist; displays 40-fold higher affinity for I 1 receptors versus α 2 -adrenoceptors. Centrally acting antihypertensive agent.

Product References

Presynaptic effects of moxonidine in isolated buffer perfused rat hearts: role of - Presynaptic effects of moxonidine in isolated buffer perfused rat hearts: role of

Schafer U, Burgdorf C, Engelhardt A, Kurz T, Richardt G. J Pharmacol Exp Ther. 2002 Dec;303(3):1163-70.

Imidazoline receptors but not alpha 2-adrenoceptors are regulated in - Imidazoline receptors but not alpha 2-adrenoceptors are regulated in

El-Ayoubi R, Menaouar A, Gutkowska J, Mukaddam-Daher S. J Pharmacol Exp Ther. 2004 Aug;310(2):446-51. Epub 2004 Apr 9.

Imidazoline receptors associated with noradrenergic terminals in the rostral - Imidazoline receptors associated with noradrenergic terminals in the rostral

Chan CK, Burke SL, Zhu H, Piletz JE, Head GA. Neuroscience. 2005;132(4):991-1007.