MPPG

• Supplier: Tocris Bioscience
• Catalog: 5033
• Prices: $189.00, $765.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 169209-65-8
• Chemical Name: (RS)-α-Methyl-4-phosphonophenylglycine
• Formula: C9H12NO5P
• Molecular Weight: 245.17
• Description: Potent antagonist of L-AP4-induced effects in rat spinal cord, thalamic and hippocampal neurons, showing selectivity over (1S,3S)-ACPD-induced effects. Potent antagonist of mGlu receptors linked to adenylyl cyclase in adult rat cortical slices.

Product References

New phenylglycine derivatives with potent and selective antagonist activity at - New phenylglycine derivatives with potent and selective antagonist activity at

Jane DE, Pittaway K, Sunter DC, Thomas NK, Watkins JC. Neuropharmacology. 1995 Aug;34(8):851-6.

Novel potent selective phenylglycine antagonists of metabotropic glutamate - Novel potent selective phenylglycine antagonists of metabotropic glutamate

Bedingfield JS, Jane DE, Kemp MC, Toms NJ, Roberts PJ. Eur J Pharmacol. 1996 Aug 1;309(1):71-8.

Pharmacological antagonism of the actions of group II and III mGluR agonists in - Pharmacological antagonism of the actions of group II and III mGluR agonists in

Bushell TJ, Jane DE, Tse HW, Watkins JC, Garthwaite J, Collingridge GL. Br J Pharmacol. 1996 Apr;117(7):1457-62.

Antagonism of the presumed presynaptic action of L-AP4 on GABAergic transmission - Antagonism of the presumed presynaptic action of L-AP4 on GABAergic transmission

Salt TE, Turner JP. Neuropharmacology. 1996 Feb;35(2):239-41.