MRS 1220

• Supplier: Tocris Bioscience
• Catalog: 4000
• Prices: $189.00, $765.00
• Sizes: 5 mg, 25 mg
• Function Type: Antagonist
• Cas Number: 183721-15-5
• Chemical Name: N-[9-Chloro-2-(2-furanyl)[1,2,4]-triazolo[1,5-c]quinazolin-5-yl]benzeneacetamide
• Formula: C21H14ClN5O2
• Molecular Weight: 403.83
• Purity: >98 %
• Description: A potent and highly selective antagonist at the human A 3 adenosine receptor (K i values are 0.65, 305, and 52 nM at hA 3 , rA 1 and rA 2A respectively. Displays an IC 50 value > 1 μ M for inhibition of binding to rat A 3 receptors).

Product References

Derivatives of the triazoloquinazoline adenosine antagonist (CGS15943) are - Derivatives of the triazoloquinazoline adenosine antagonist (CGS15943) are

Kim YC, Ji XD, Jacobson KA. J Med Chem. 1996 Oct 11;39(21):4142-8.

Pharmacological characterization of novel A3 adenosine receptor-selective - Pharmacological characterization of novel A3 adenosine receptor-selective

Jacobson KA, Park KS, Jiang JL, Kim YC, Olah ME, Stiles GL, Ji XD. Neuropharmacology. 1997 Sep;36(9):1157-65.

Derivatives of the triazoloquinazoline adenosine antagonist (CGS 15943) having - Derivatives of the triazoloquinazoline adenosine antagonist (CGS 15943) having

Kim YC, de Zwart M, Chang L, Moro S, von Frijtag Drabbe Kunzel JK, Melman N, IJzerman AP, Jacobson KA. J Med Chem. 1998 Jul 16;41(15):2835-45.