MRS 1334

• Supplier: Tocris Bioscience
• Catalog: 1217
• Prices: $165.00, $685.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 192053-05-7
• Chemical Name: 1,4-Dihydro-2-methyl-6-phenyl-4-(phenylethynyl)-3,5-pyridinedicarboxylicacid3-ethyl-5-[(3-nitrophenyl)methyl]ester
• Formula: C31H26N2O6
• Molecular Weight: 522.56
• Purity: >98 %
• Description: Potent and highly selective antagonist for the human adenosine A 3 receptor. K i values are 2.69 nM at hA 3 , and > 100 μ M at rat A 1 and rat A 2A receptors.

Product References

Structure-activity relationships and molecular modeling of 3, - Structure-activity relationships and molecular modeling of 3,

Li AH, Moro S, Melman N, Ji XD, Jacobson KA. J Med Chem. 1998 Aug 13;41(17):3186-201.

New potent and selective human adenosine A(3) receptor antagonists. - New potent and selective human adenosine A(3) receptor antagonists.

Baraldi PG, Borea PA. Trends Pharmacol Sci. 2000 Dec;21(12):456-9.