MRS 1706

• Supplier: Tocris Bioscience
• Catalog: 5246
• Prices: $175.00, $709.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 264622-53-9
• Chemical Name: N-(4-Acetylphenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]acetamide
• Formula: C27H29N5O5
• Molecular Weight: 503.56
• Purity: >96 %
• Description: Potent and selective adenosine A 2B receptor inverse agonist (K i values are 1.39, 157, 112 and 230 nM for human A 2B , A 1 , A 2A and A 3 receptors respectively).

Product References

Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent - Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent

Kim YC, Ji X, Melman N, Linden J, Jacobson KA. J Med Chem. 2000 Mar 23;43(6):1165-72.

ZM241385, DPCPX, MRS1706 are inverse agonists with different relative intrinsic - ZM241385, DPCPX, MRS1706 are inverse agonists with different relative intrinsic

Li Q, Ye K, Blad CC, den Dulk H, Brouwer J, Ijzerman AP, Beukers MW. J Pharmacol Exp Ther. 2007 Feb;320(2):637-45. Epub 2006 Oct 31.