MRS 1754

• Supplier: Tocris Bioscience
• Catalog: 1584
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 264622-58-4
• Chemical Name: N-(4-Cyanophenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide
• Formula: C26H26N6O4
• Molecular Weight: 486.52
• Purity: >98 %
• Description: Selective adenosine A 2B receptor antagonist (K i values are 1.97, 16.8, 403, 503, 570 and 612 nM for hA 2B , rA 1 , hA 1 , hA 2A , hA 3 and rA 2A receptors respectively).

Product References

Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent - Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent

Kim YC, Ji X, Melman N, Linden J, Jacobson KA. J Med Chem. 2000 Mar 23;43(6):1165-72.

[3H]MRS 1754, a selective antagonist radioligand for A(2B) adenosine receptors. - [3H]MRS 1754, a selective antagonist radioligand for A(2B) adenosine receptors.

Ji X, Kim YC, Ahern DG, Linden J, Jacobson KA. Biochem Pharmacol. 2001 Mar 15;61(6):657-63.