MRS 2693 trisodium salt

• Supplier: Tocris Bioscience
• Catalog: 2915
• Prices: $235.00
• Sizes: 1 mg
• Function Type: Agonist
• Cas Number: 1448858-83-0
• Chemical Name: 5-Iodouridine-5'-O-diphosphatetrisodiumsalt
• Formula: C9H10IN2Na3O12P2
• Molecular Weight: 596
• Purity: >95 %
• Description: Selective P2Y 6 agonist (EC 50 = 0.015 μ M at the hP2Y 6 receptor). Displays no activity at other P2Y subtypes. Exerts a cytoprotective effect in an in vivo mouse model of hindlimb skeletal muscle ischemia/reperfusion injury.

Product References

Structure-activity relationships of uridine 5'-diphosphate analogues at the human - Structure-activity relationships of uridine 5'-diphosphate analogues at the human

Besada P, Shin DH, Costanzi S, Ko H, Mathe C, Gagneron J, Gosselin G, Maddileti S, Harden TK, Jacobson KA. J Med Chem. 2006 Sep 7;49(18):5532-43.

Attenuation of apoptosis in vitro and ischemia/reperfusion injury in vivo in - Attenuation of apoptosis in vitro and ischemia/reperfusion injury in vivo in

Mamedova LK, Wang R, Besada P, Liang BT, Jacobson KA. Pharmacol Res. 2008 Sep-Oct;58(3-4):232-9.