[D-Trp 8 ]- γ -MSH

• Supplier: Tocris Bioscience
• Catalog: 3424
• Prices: $165.00
• Sizes: 1 mg
• Function Type: Agonist
• Cas Number: 321351-81-9
• Formula: C74H99N21O16S
• Molecular Weight: 1570.79
• Description: Selective melanocortin 3 (MC 3 ) receptor agonist (IC 50 values are 6.7, 340 and 600 nM for human MC 3 , MC 5 and MC 4 receptors respectively). Displays anti-inflammatory efficacy.

Product References

D-Amino acid scan of gamma-melanocyte-stimulating hormone: importance of Trp(8) - D-Amino acid scan of gamma-melanocyte-stimulating hormone: importance of Trp(8)

Grieco P, Balse PM, Weinberg D, MacNeil T, Hruby VJ. J Med Chem. 2000 Dec 28;43(26):4998-5002.

[D-Trp8]-gamma-melanocyte-stimulating hormone exhibits anti-inflammatory efficacy - [D-Trp8]-gamma-melanocyte-stimulating hormone exhibits anti-inflammatory efficacy

Getting SJ, Lam CW, Leoni G, Gavins FN, Grieco P, Perretti M. Mol Pharmacol. 2006 Dec;70(6):1850-5. Epub 2006 Sep 7.

Anti-inflammatory and antiosteoclastogenesis properties of endogenous - Anti-inflammatory and antiosteoclastogenesis properties of endogenous

Patel HB, Bombardieri M, Sampaio AL, D'Acquisto F, Gray M, Grieco P, Getting SJ, Pitzalis C, Perretti M. FASEB J. 2010 Dec;24(12):4835-43.