α -MSH

Name α -MSH
Supplier Tocris Bioscience
Catalog 4272
Prices $75.00
Sizes 1 mg
Function Type Agonist
Cas Number 581-05-5
Formula C77H109N21O19S
Molecular Weight 1664.9
Description Endogenous melanocortin receptor agonist (K i values are 0.12, 31, 660 and 5700 nM for MC 1 , MC 3 , MC 4 and MC 5 receptors respectively). Anti-inflammatory peptide; antagonizes proinflammatory mediators, including TNF- α , IL-6 and NO and induces anti-inflammatory cytokine IL-10. Inhibits food intake and induces penile erections following i.c.v. administration.
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Product References

Melanocortin receptors: perspectives for novel drugs. - Melanocortin receptors: perspectives for novel drugs.

Wikberg JE. Eur J Pharmacol. 1999 Jun 30;375(1-3):295-310.

alpha-Melanocyte stimulating hormone and oxytocin induced penile erections, and - alpha-Melanocyte stimulating hormone and oxytocin induced penile erections, and

Mizusawa H, Hedlund P, Andersson KE. J Urol. 2002 Feb;167(2 Pt 1):757-60.

Central neurotranspeptide, alpha-melanocyte-stimulating hormone (alpha-MSH) is - Central neurotranspeptide, alpha-melanocyte-stimulating hormone (alpha-MSH) is

Yamaoka-Tojo M, Tojo T, Shioi T, Masuda T, Inomata T, Izumi T. Intern Med. 2006;45(7):429-34. Epub 2006 May 1.