Mycophenolic acid

• Supplier: Tocris Bioscience
• Catalog: 4102
• Prices: $115.00
• Sizes: 100 mg
• Cas Number: 24280-93-1
• Chemical Name: 6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoicacid
• Formula: C17H20O6
• Molecular Weight: 320.34
• Purity: >98 %
• Description: Immunosuppressive agent with antiviral and antitumor effects in vitro and in vivo . Potently inhibits inosine monophosphate dehydrogenase, thus inhibiting de novo GTP synthesis leading to decreased RNA and DNA synthesis. Reversibly inhibits proliferation of T and B lymphocytes and antibody formation.

Product References

Lymphocyte-selective cytostatic and immunosuppressive effects of mycophenolic - Lymphocyte-selective cytostatic and immunosuppressive effects of mycophenolic

Eugui EM, Almquist SJ, Muller CD, Allison AC. Scand J Immunol. 1991 Feb;33(2):161-73.

Mechanisms of action of mycophenolic acid. - Mechanisms of action of mycophenolic acid.

Allison AC, Kowalski WJ, Muller CD, Eugui EM. Ann N Y Acad Sci. 1993 Nov 30;696:63-87.

Mycophenolic acid, an inhibitor of IMP dehydrogenase that is also an - Mycophenolic acid, an inhibitor of IMP dehydrogenase that is also an

Senda M, DeLustro B, Eugui E, Natsumeda Y. Transplantation. 1995 Nov 27;60(10):1143-8.

Distinct inhibitory effects of spinal endomorphin-1 and endomorphin-2 on evoked - Distinct inhibitory effects of spinal endomorphin-1 and endomorphin-2 on evoked

Chapman V, Diaz A, Dickenson AH. Br J Pharmacol. 1997 Dec;122(8):1537-9.

A potent and selective endogenous agonist for the mu-opiate receptor. - A potent and selective endogenous agonist for the mu-opiate receptor.

Zadina JE, Hackler L, Ge LJ, Kastin AJ. Nature. 1997 Apr 3;386(6624):499-502.

Pharmacological characterization of endomorphin-1 and endomorphin-2 in mouse - Pharmacological characterization of endomorphin-1 and endomorphin-2 in mouse

Goldberg IE, Rossi GC, Letchworth SR, Mathis JP, Ryan-Moro J, Leventhal L, Su W, Emmel D, Bolan EA, Pasternak GW. J Pharmacol Exp Ther. 1998 Aug;286(2):1007-13.