NADA

• Supplier: Tocris Bioscience
• Catalog: 3282
• Prices: $109.00, $459.00
• Sizes: 5 mg, 25 mg
• Function Type: Agonist
• Cas Number: 199875-69-9
• Chemical Name: N-[2-(3,4-Dihydroxyphenyl)ethyl]-5Z,8Z,11Z,14Z-eicosatetraenamide
• Formula: C28H41NO3
• Molecular Weight: 439.64
• Description: Potent endogenous cannabinoid and vanilloid receptor agonist, with no action at dopamine receptors. Selective for CB 1 over CB 2 receptors (K i values are 0.25 and 12 μ M respectively), and potent agonist at TRPV1 (VR1) receptors (EC 50 ~ 50 nM). Metabolically stable and competitively inhibits FAAH and anandamide transport. Has cannabinoid and vanilloid actions in vivo .

Product References

N-acyl-dopamines: novel synthetic CB(1) cannabinoid-receptor ligands and - N-acyl-dopamines: novel synthetic CB(1) cannabinoid-receptor ligands and

Bisogno T, Melck D, Bobrov MYu, Gretskaya NM, Bezuglov VV, De Petrocellis L, Di Marzo V. Biochem J. 2000 Nov 1;351 Pt 3:817-24.

Overlap between the ligand recognition properties of the anandamide transporter - Overlap between the ligand recognition properties of the anandamide transporter

De Petrocellis L, Bisogno T, Davis JB, Pertwee RG, Di Marzo V. FEBS Lett. 2000 Oct 13;483(1):52-6.

An endogenous capsaicin-like substance with high potency at recombinant and - An endogenous capsaicin-like substance with high potency at recombinant and

Huang SM, Bisogno T, Trevisani M, Al-Hayani A, De Petrocellis L, Fezza F, Tognetto M, Petros TJ, Krey JF, Chu CJ, Miller JD, Davies SN, Geppetti P, Walker JM, Di Marzo V. Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8400-5.