Nafamostat mesylate

• Supplier: Tocris Bioscience
• Catalog: 1347
• Prices: $89.00, $375.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 82956-11-4
• Chemical Name: 4-[(Aminoiminomethyl)amino]benzoicacid6-(aminoiminomethyl)-2-naphthalenylesterdimethanesulfonate
• Formula: C19H17N5O2.2CH4O3S
• Molecular Weight: 539.59
• Purity: >99 %
• Description: Broad spectrum serine protease inhibitor. Displays selectivity for human tryptase when used at relatively low concentrations. Reduces eosinophil infiltration, mast cell activation and airway responsiveness in a murine model of asthma.

Product References

Nafamostat mesilate is an extremely potent inhibitor of human tryptase. - Nafamostat mesilate is an extremely potent inhibitor of human tryptase.

Mori S, Itoh Y, Shinohata R, Sendo T, Oishi R, Nishibori M. J Pharmacol Sci. 2003 Aug;92(4):420-3.

A potent tryptase inhibitor nafamostat mesilate dramatically suppressed pulmonary - A potent tryptase inhibitor nafamostat mesilate dramatically suppressed pulmonary

Sendo T, Itoh Y, Goromaru T, Sumimura T, Saito M, Aki K, Yano T, Oishi R. Br J Pharmacol. 2003 Mar;138(5):959-67.

Serine protease inhibitors nafamostat mesilate and gabexate mesilate attenuate - Serine protease inhibitors nafamostat mesilate and gabexate mesilate attenuate

Chen CL, Wang SD, Zeng ZY, Lin KJ, Kao ST, Tani T, Yu CK, Wang JY. J Allergy Clin Immunol. 2006 Jul;118(1):105-12. Epub 2006 May 2.