NCH 51

• Supplier: Tocris Bioscience
• Catalog: 1044
• Prices: $169.00, $705.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 848354-66-5
• Chemical Name: 2-MethylpropanethioicacidS-[7-oxo-7-[(4-phenyl-2-thiazolyl)amino]heptyl]ester
• Formula: C20H26N2O2S2
• Molecular Weight: 390.56
• Purity: >98 %
• Description: Histone deacetylase (HDAC) inhibitor. Inhibits growth of various cancer cells in vitro (EC 50 = 1.1 - 9.1 μ M).

Product References

Novel inhibitors of human histone deacetylases: design, synthesis, enzyme - Novel inhibitors of human histone deacetylases: design, synthesis, enzyme

Suzuki T, Nagano Y, Kouketsu A, Matsuura A, Maruyama S, Kurotaki M, Nakagawa H, Miyata N. J Med Chem. 2005 Feb 24;48(4):1019-32.

Proteome analyses of the growth inhibitory effects of NCH-51, a novel histone - Proteome analyses of the growth inhibitory effects of NCH-51, a novel histone

Sanda T, Okamoto T, Uchida Y, Nakagawa H, Iida S, Kayukawa S, Suzuki T, Oshizawa T, Suzuki T, Miyata N, Ueda R. Leukemia. 2007 Nov;21(11):2344-53. Epub 2007 Aug 9.