| Name | NCX 466 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4531 |
| Prices | $165.00 |
| Sizes | 10 mg |
| Cas Number | 1262956-64-8 |
| Chemical Name | (αS)-6-Methoxy-α-methyl-2-naphthaleneaceticacid(5S)-5,6-bis(nitrooxy)hexylester |
| Formula | C20H24N2O9 |
| Molecular Weight | 436.41 |
| Purity | >98 % |
| Description | Cyclooxygenase (COX)-inhibiting nitric oxide (NO) donor (CINOD). Inhibits COX-1 and COX-2 while releasing NO. Demonstrates higher efficacy than naproxen, its congener drug, in reducing levels of profibrotic cytokine transforming growth factor- β and oxidative stress in a mouse model of bleomycin-induced lung fibrosis. Orally available. |
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