NE 100 hydrochloride

Name NE 100 hydrochloride
Supplier Tocris Bioscience
Catalog 3333
Prices $155.00, $645.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 149409-57-4
Chemical Name 4-Methoxy-3-(2-phenylethoxy)-N,N-dipropylbenzeneethanaminehydrochloride
Formula C23H33NO2.HCl
Molecular Weight 391.97
Purity >98 %
Description Potent and selective σ 1 receptor antagonist (K i = 0.86 nM) that displays > 55-fold selectivity over σ 2 receptors and > 6000-fold selectivity over D 1 , D 2 , 5-HT 1A , 5-HT 2 and PCP receptors. Exhibits reversible binding (K d = 1.2 nM) and displays antipsychotic activity in vivo . Orally active.
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