Name | cis -Ned 19 |
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Supplier | Tocris Bioscience |
Catalog | 5025 |
Prices | $299.00 |
Sizes | 10 mg |
Function Type | Antagonist |
Cas Number | 1137264-00-6 |
Chemical Name | (1S,3S)-1-[3-[[4-(2-Fluorophenyl)piperazin-1-yl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylicacid |
Formula | C30H31FN4O3 |
Molecular Weight | 514.59 |
Purity | >97 % |
Description | Irreversible nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist; inhibits Ca 2+ release (IC 50 = 800 nM) and [ 32 P]NAADP binding (IC 50 = 15 μ M). Stereoisomer of trans -Ned 19 (Cat. No. 3954). Fluorescently labels NAADP receptors in intact cells (excitation 351 and 365 nm using an ultraviolet Argon laser). |
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