Neuromedin U (rat)

• Supplier: Tocris Bioscience
• Catalog: 3648
• Prices: $209.00
• Sizes: 1 mg
• Cas Number: 117505-80-3
• Formula: C124H180N34O31
• Molecular Weight: 2643
• Description: Endogenous peptide regulating blood pressure, ion transport in the gut, mesenteric blood flow and adrenocortical function. Also decreases food intake and body weight, increases body temperature and heat production, and inhibits gastric acid secretion via the CRH system following central administration in vivo .

Product References

Neuromedins: novel smooth-muscle stimulating peptides identified in porcine - Neuromedins: novel smooth-muscle stimulating peptides identified in porcine

Minamino N, Sudoh T, Kangawa K, Matsuo H. Peptides. 1985;6 Suppl 3:245-8.

Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3. - Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3.

Szekeres PG, Muir AI, Spinage LD, Miller JE, Butler SI, Smith A, Rennie GI, Murdock PR, Fitzgerald LR, Wu Hl, McMillan LJ, Guerrera S, Vawter L, Elshourbagy NA, Mooney JL, Bergsma DJ, Wilson S, Chambers JK. J Biol Chem. 2000 Jul 7;275(27):20247-50.

Neuromedin U acts in the central nervous system to inhibit gastric acid secretion - Neuromedin U acts in the central nervous system to inhibit gastric acid secretion

Mondal MS, Date Y, Murakami N, Toshinai K, Shimbara T, Kangawa K, Nakazato M. Am J Physiol Gastrointest Liver Physiol. 2003 Jun;284(6):G963-9. Epub 2003 Feb