NFAT Inhibitor

Name NFAT Inhibitor
Supplier Tocris Bioscience
Catalog 3892
Prices $205.00
Sizes 1 mg
Function Type Inhibitor
Cas Number 249537-73-3
Formula C75H118N20O22S
Molecular Weight 1683.94
Description Selective inhibitor of calcineurin-mediated dephosphorylation of nuclear factor of activated T cells (NFAT). Does not disrupt other calcineurin-dependent pathways. Inhibits NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells.
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Product References

Affinity-driven peptide selection of an NFAT inhibitor more selective than - Affinity-driven peptide selection of an NFAT inhibitor more selective than

Aramburu J, Yaffe MB, Lopez-Rodriguez C, Cantley LC, Hogan PG, Rao A. Science. 1999 Sep 24;285(5436):2129-33.

Microglial phenotype is regulated by activity of the transcription factor, NFAT - Microglial phenotype is regulated by activity of the transcription factor, NFAT

Nagamoto-Combs K, Combs CK. J Neurosci. 2010 Jul 14;30(28):9641-6.