NGD 94-1

• Supplier: Tocris Bioscience
• Catalog: 2635
• Prices: $159.00, $665.00
• Sizes: 10 mg, 50 mg
• Cas Number: 178928-68-2
• Chemical Name: 2-[4-[(2-Phenyl-1H-imidazol-5-yl)methyl]-1-piperazinyl]-pyrimidine
• Formula: C18H20N6
• Molecular Weight: 320.39
• Purity: >99 %
• Description: High affinity D 4 receptor ligand; selective over D 1 , D 2 , D 3 and D 5 receptors. Displays antagonist activity at the human D 4.2 receptor (K i = 3.6 nM in transfected CHO cells) and exhibits agonist activity at the D 4.4 receptor in HEK 293 cells.

Product References

II. Localization and characterization of dopamine D4 binding sites in rat and - II. Localization and characterization of dopamine D4 binding sites in rat and

Primus RJ, Thurkauf A, Xu J, Yevich E, McInerney S, Shaw K, Tallman JF, Gallagher DW. J Pharmacol Exp Ther. 1997 Aug;282(2):1020-7.

I. NGD 94-1: identification of a novel, high-affinity antagonist at the human - I. NGD 94-1: identification of a novel, high-affinity antagonist at the human

Tallman JF, Primus RJ, Brodbeck R, Cornfield L, Meade R, Woodruff K, Ross P, Thurkauf A, Gallager DW. J Pharmacol Exp Ther. 1997 Aug;282(2):1011-9.

NGD 94-1 as an agonist at human recombinant dopamine D4.4 receptors expressed in - NGD 94-1 as an agonist at human recombinant dopamine D4.4 receptors expressed in

Gazi L, Sommer B, Nozulak J, Schoeffter P. Eur J Pharmacol. 1999 May 21;372(3):R9-10.