(-)-Nicotine ditartrate

• Supplier: Tocris Bioscience
• Catalog: 4106
• Prices: $65.00
• Sizes: 50 mg
• Function Type: Agonist
• Cas Number: 65-31-6
• Chemical Name: (S)-(-)-1-Methyl-2-(3-pyridyl)pyrrolidine(+)-ditartratesalt
• Formula: C10H14N2.2C4H6O6
• Molecular Weight: 462.41
• Purity: >99 %
• Description: Nicotinic acetylcholine receptor (nAChR) agonist (K i values are 1, > 1000, 4000 and 7130 nM at α 4 β 2, α 1 β 1 δ γ , rat α 7 and human α 7 respectively). Exhibits vasoconstrictive, hypertensive and prothrombotic activity in vivo .

Product References

ABT-594 [(R)-5-(2-azetidinylmethoxy)-2-chloropyridine]: a novel, orally effective - ABT-594 [(R)-5-(2-azetidinylmethoxy)-2-chloropyridine]: a novel, orally effective

Donnelly-Roberts DL, Puttfarcken PS, Kuntzweiler TA, Briggs CA, Anderson DJ, Campbell JE, Piattoni-Kaplan M, McKenna DG, Wasicak JT, Holladay MW, Williams M, Arneric SP. J Pharmacol Exp Ther. 1998 May;285(2):777-86.

Rat alpha3/beta4 subtype of neuronal nicotinic acetylcholine receptor stably - Rat alpha3/beta4 subtype of neuronal nicotinic acetylcholine receptor stably

Xiao Y, Meyer EL, Thompson JM, Surin A, Wroblewski J, Kellar KJ. Mol Pharmacol. 1998 Aug;54(2):322-33.

Acute infusion of nicotine potentiates norepinephrine-induced vasoconstriction in - Acute infusion of nicotine potentiates norepinephrine-induced vasoconstriction in

Mayhan WG. J Lab Clin Med. 1999 Jan;133(1):48-54.