Nigericin sodium salt

Name Nigericin sodium salt
Supplier Tocris Bioscience
Catalog 4112
Prices $79.00
Sizes 10 mg
Cas Number 28643-80-3
Chemical Name (2R)-2-[(2R,3S,6R)-6-[[(2S,4R,5R,7R,9R,10R)-2-[(2R,5S)-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-Hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2-tetrahydropyranyl]-3-methyl-2-tetrahydrofuranyl]-5-methyl-2-tetrahydrofuranyl]-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]decan-7-yl]methyl]-3-methyl-2-tetrahydropyranyl]propanoicacidsodiumsalt
Formula C40H67NaO11
Molecular Weight 746.94
Description Potassium ionophore, exchanges K + for H + across biological membranes, in a similar manner to Valinomycin (Cat. No. 3373). Stimulates mitochondral ATPase activity and disrupts membrane potential. Also acts as an ionophore for Pb 2+ with no activity with other divalent cations. Antibiotic derived from Streptomyces hygroscopius .
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