Nilutamide

• Supplier: Tocris Bioscience
• Catalog: 1139
• Prices: $95.00
• Sizes: 100 mg
• Cas Number: 63612-50-0
• Chemical Name: 5,5-Dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedione
• Formula: C12H10F3N3O4
• Molecular Weight: 317.22
• Purity: >99 %
• Description: Non-steroidal and silent antiandrogen. Binds to androgen receptors and also inhibits androgen biosynthesis in vitro . In rats in vivo it inhibits androgen-induced prostate weight increase and inhibits negative androgen-dependent gonadotropin feedback leading to an increase in luteinising hormone and testosterone. Orally active.

Product References

Action of a non-steroid anti-androgen, RU 23908, in peripheral and central - Action of a non-steroid anti-androgen, RU 23908, in peripheral and central

Raynaud JP, Bonne C, Bouton MM, Lagace L, Labrie F. J Steroid Biochem. 1979 Jul;11(1A):93-9.

The pure antiandrogen RU 23908 (Anandron), a candidate of choice for the combined - The pure antiandrogen RU 23908 (Anandron), a candidate of choice for the combined

Raynaud JP, Bonne C, Moguilewsky M, Lefebvre FA, Belanger A, Labrie F. Prostate. 1984;5(3):299-311.

Pharmacology and clinical studies with RU 23908 (Anandron). - Pharmacology and clinical studies with RU 23908 (Anandron).

Raynaud JP, Moguilewsky M, Tournemine C, Pottier J, Coussediere D, Salmon J, Husson JM, Bertagna C, Tremblay D, Pendyala L, et al.. Prog Clin Biol Res. 1985;185A:99-120.

Inhibition of rat testicular 17 alpha-hydroxylase and 17,20-lyase activities by - Inhibition of rat testicular 17 alpha-hydroxylase and 17,20-lyase activities by

Ayub M, Levell MJ. J Steroid Biochem. 1987 Jul;28(1):43-7.