3-Nitropropionic acid

• Supplier: Tocris Bioscience
• Catalog: 0602
• Prices: $49.00
• Sizes: 50 mg
• Function Type: Inhibitor
• Cas Number: 504-88-1
• Formula: C3H5NO4
• Molecular Weight: 119.08
• Purity: >97 %
• Description: Irreversible mitochondrial respiratory complex II (succinate dehydrogenase) inhibitor; induces autophagy in SH-SY5Y cells. Recapitulates Huntington's disease-like pathology and symptoms in primate and rodent models.

Product References

3-nitropropionic acid is a suicide inhibitor of mitochondrial respiration that, - 3-nitropropionic acid is a suicide inhibitor of mitochondrial respiration that,

Huang LS, Sun G, Cobessi D, Wang AC, Shen JT, Tung EY, Anderson VE, Berry EA. J Biol Chem. 2006 Mar 3;281(9):5965-72. Epub 2005 Dec 21.

Mitochondrial impairment induced by 3-nitropropionic acid is enhanced by - Mitochondrial impairment induced by 3-nitropropionic acid is enhanced by

de Oca Balderas PM, Ospina GG, Del Angel AS. Neurosci Lett. 2013 Jun 24;546:16-20.

3-Nitropropionic acid induces autophagy by forming mitochondrial permeability - 3-Nitropropionic acid induces autophagy by forming mitochondrial permeability

Solesio ME, Saez-Atienzar S, Jordan J, Galindo MF. Br J Pharmacol. 2013 Jan;168(1):63-75.