NKY 80

• Supplier: Tocris Bioscience
• Catalog: 1603
• Prices: $129.00, $535.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 299442-43-6
• Chemical Name: 2-Amino-7-(2-furanyl)-7,8-dihydro-5(6H)-quinazolinone
• Formula: C12H11N3O2
• Molecular Weight: 229.23
• Purity: >98 %
• Description: Inhibitor of adenylyl cyclase (AC). Exhibits greater affinity for AC5 over AC3 and AC2 (IC 50 values are 8.3 μ M, 132 μ M and 1.7 mM respectively).

Product References

Type-specific regulation of adenylyl cyclase. Selective pharmacological - Type-specific regulation of adenylyl cyclase. Selective pharmacological

Onda T, Hashimoto Y, Nagai M, Kuramochi H, Saito S, Yamazaki H, Toya Y, Sakai I, Homcy CJ, Nishikawa K, Ishikawa Y. J Biol Chem. 2001 Dec 21;276(51):47785-93. Epub 2001 Oct 15.

Capturing adenylyl cyclases as potential drug targets. - Capturing adenylyl cyclases as potential drug targets.

Pierre S, Eschenhagen T, Geisslinger G, Scholich K. Nat Rev Drug Discov. 2009 Apr;8(4):321-35.