Nociceptin

• Supplier: Tocris Bioscience
• Catalog: 1779
• Prices: $139.00
• Sizes: 1 mg
• Cas Number: 170713-75-4
• Formula: C79H129N27O22
• Molecular Weight: 1809
• Description: Endogenous ligand for the NOP opioid receptor (pK i = 8.6). Has no significant activity at μ , δ or κ opioid receptors (pK i < 6).

Product References

Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 - Isolation and structure of the endogenous agonist of opioid receptor-like ORL1

Meunier JC, Mollereau C, Toll L, Suaudeau C, Moisand C, Alvinerie P, Butour JL, Guillemot JC, Ferrara P, Monsarrat B, et al.. Nature. 1995 Oct 12;377(6549):532-5.

Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled - Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled

Reinscheid RK, Nothacker HP, Bourson A, Ardati A, Henningsen RA, Bunzow JR, Grandy DK, Langen H, Monsma FJ Jr, Civelli O. Science. 1995 Nov 3;270(5237):792-4.

The orphan opioid receptor and its endogenous ligand--nociceptin/orphanin FQ. - The orphan opioid receptor and its endogenous ligand--nociceptin/orphanin FQ.

Henderson G, McKnight AT. Trends Pharmacol Sci. 1997 Aug;18(8):293-300.

Structure-activity relationships of nociceptin and related peptides: comparison - Structure-activity relationships of nociceptin and related peptides: comparison

Guerrini R, Calo' G, Rizzi A, Bigoni R, Rizzi D, Regoli D, Salvadori S. Peptides. 2000 Jul;21(7):923-33.