[Phe 1 Ψ (CH 2 -NH)Gly 2 ]Nociceptin(1-13)NH 2

• Supplier: Tocris Bioscience
• Catalog: 1308
• Prices: $319.00
• Sizes: 1 mg
• Function Type: Agonist
• Cas Number: 213130-17-7
• Formula: C61H102N22O14
• Molecular Weight: 1367.6
• Description: Potent agonist of the nociceptin (ORL 1 ) receptor, demonstrated both in vitro and in vivo . Selective, competitive antagonism at the nociceptin receptor has also been reported (pA 2 = 7.02 and 6.75 in the guinea pig ileum and mouse vas deferens respectively).

Product References

Address and message sequences for the nociceptin receptor: a structure-activity - Address and message sequences for the nociceptin receptor: a structure-activity

Guerrini R, Calo G, Rizzi A, Bianchi C, Lazarus LH, Salvadori S, Temussi PA, Regoli D. J Med Chem. 1997 Jun 6;40(12):1789-93.

A new selective antagonist of the nociceptin receptor. - A new selective antagonist of the nociceptin receptor.

Guerrini R, Calo G, Rizzi A, Bigoni R, Bianchi C, Salvadori S, Regoli D. Br J Pharmacol. 1998 Jan;123(2):163-5.

[Phe1psi(CH2-NH)Gly2]-nociceptin-(1-13)NH2, a proposed antagonist of the - [Phe1psi(CH2-NH)Gly2]-nociceptin-(1-13)NH2, a proposed antagonist of the

Xu IS, Wiesenfeld-Hallin Z, Xu XJ. Neurosci Lett. 1998 Jun 19;249(2-3):127-30.

Comparison of the effects of [Phe1psi(CH2-NH)Gly2]nociceptin(1-13)NH2 in rat - Comparison of the effects of [Phe1psi(CH2-NH)Gly2]nociceptin(1-13)NH2 in rat

Okawa H, Nicol B, Bigoni R, Hirst RA, Calo G, Guerrini R, Rowbotham DJ, Smart D, McKnight AT, Lambert DG. Br J Pharmacol. 1999 May;127(1):123-30.