Nocistatin (bovine)

• Supplier: Tocris Bioscience
• Catalog: 1119
• Prices: $209.00
• Sizes: 1 mg
• Cas Number: 208253-85-4
• Formula: C82H135N21O32
• Molecular Weight: 1927.07
• Description: An endogenous peptide derived from the same precursor as nociceptin, which is able to block nociceptin-induced allodynia and hyperalgesia and may play an opposing role in pain transmission. Shown to reverse nociceptin inhibition of glutamate release from rat brain slices; also modulates 5-HT transmission in the mouse neocortex via mechanisms separate from nociceptin/orphanin FQ.

Product References

Nocistatin reverses nociceptin inhibition of glutamate release from rat brain - Nocistatin reverses nociceptin inhibition of glutamate release from rat brain

Nicol B, Lambert DG, Rowbotham DJ, Okuda-Ashitaka E, Ito S, Smart D, McKnight AT. Eur J Pharmacol. 1998 Sep 4;356(2-3):R1-3.

Nocistatin, a peptide that blocks nociceptin action in pain transmission. - Nocistatin, a peptide that blocks nociceptin action in pain transmission.

Okuda-Ashitaka E, Minami T, Tachibana S, Yoshihara Y, Nishiuchi Y, Kimura T, Ito S. Nature. 1998 Mar 19;392(6673):286-9.

Effect of nocistatin and its interaction with nociceptin/orphanin FQ on the rat - Effect of nocistatin and its interaction with nociceptin/orphanin FQ on the rat

Yamamoto T, Sakashita Y. Neurosci Lett. 1999 Mar 12;262(3):179-82.

Nocistatin inhibits 5-hydroxytryptamine release in the mouse neocortex via - Nocistatin inhibits 5-hydroxytryptamine release in the mouse neocortex via

Fantin M, Fischetti C, Trapella C, Morari M. Br J Pharmacol. 2007 Oct;152(4):549-55. Epub 2007 Jul 9.