Nocodazole

• Supplier: Tocris Bioscience
• Catalog: 1198
• Prices: $95.00
• Sizes: 10 mg
• Function Type: Inhibitor
• Cas Number: 31430-18-9
• Chemical Name: [5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]carbonicacid,methylester
• Formula: C14H11N3O3S
• Molecular Weight: 301.32
• Purity: >95 %
• Description: Microtubule inhibitor; inhibits mitosis. Also inhibits autophagosome-lysosome fusion. Enhances homology-directed repair (HDR) efficiency 9 to 31% (depending on cell cycle phase) and increases Cas9-mediated gene editing frequencies.

Product References

Nanomolar concentrations of nocodazole alter microtubule dynamic instability in - Nanomolar concentrations of nocodazole alter microtubule dynamic instability in

Vasquez RJ, Howell B, Yvon AM, Wadsworth P, Cassimeris L. Mol Biol Cell. 1997 Jun;8(6):973-85.

Relationship between microtubule dynamics and lamellipodium formation revealed by - Relationship between microtubule dynamics and lamellipodium formation revealed by

Mikhailov A, Gundersen GG. Cell Motil Cytoskeleton. 1998;41(4):325-40.

Microtubule disruption inhibits autophagosome-lysosome fusion: implications for - Microtubule disruption inhibits autophagosome-lysosome fusion: implications for

Webb JL, Ravikumar B, Rubinsztein DC. Int J Biochem Cell Biol. 2004 Dec;36(12):2541-50.

Methods in mammalian autophagy research. - Methods in mammalian autophagy research.

Mizushima N, Yoshimori T, Levine B. Cell. 2010 Feb 5;140(3):313-26.