5-Nonyloxytryptamine oxalate

• Supplier: Tocris Bioscience
• Catalog: 3691
• Prices: $159.00, $665.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 157798-13-5
• Formula: C19H30N2O.C2H2O4
• Molecular Weight: 392.49
• Purity: >99 %
• Description: 5-HT 1B selective agonist, several times more potent than sumatriptan and inactive as a 5-HT 1A agonist (K i at 5-HT 1B = 1 nM, selectivity over 5-HT 1A > 300-fold). Mimics polysialic acid activity, stimulates neuritogenesis, myelination and Schwann cell migration in vitro .

Product References

5-(Nonyloxy)tryptamine: a novel high-affinity 5-HT1D beta serotonin receptor - 5-(Nonyloxy)tryptamine: a novel high-affinity 5-HT1D beta serotonin receptor

Glennon RA, Hong SS, Dukat M, Teitler M, Davis K. J Med Chem. 1994 Sep 2;37(18):2828-30.

Binding of O-alkyl derivatives of serotonin at human 5-HT1D beta receptors. - Binding of O-alkyl derivatives of serotonin at human 5-HT1D beta receptors.

Glennon RA, Hong SS, Bondarev M, Law H, Dukat M, Rakhi S, Power P, Fan E, Kinneau D, Kamboj R, Teitler M, Herrick-Davis K, Smith C. J Med Chem. 1996 Jan 5;39(1):314-22.

Nonyloxytryptamine mimics polysialic acid and modulates neuronal and glial - Nonyloxytryptamine mimics polysialic acid and modulates neuronal and glial

Loers G, Saini V, Mishra B, Papastefanaki F, Lutz D, Chaudhury S, Ripoll DR, Wallqvist A, Gul S, Schachner M, Kaur G. J Neurochem. 2014 Jan;128(1):88-100.