Name | Novokinin |
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Supplier | Tocris Bioscience |
Catalog | 1697 |
Prices | $139.00 |
Sizes | 1 mg |
Function Type | Agonist |
Cas Number | 358738-77-9 |
Formula | C39H61N11O7 |
Molecular Weight | 795.98 |
Description | Angiotensin AT 2 receptor agonist (K i = 7.35 μ M) that displays 93-fold selectivity over AT 1 . Exhibits vasorelaxing and hypotensive activity via activation of the IP (prostacyclin) receptor, and suppresses food intake via activation of PGE 2 -EP 4 . Orally active. |
Supplier Page | Shop |
Yamada Y, Yamauchi D, Yokoo M, Ohinata K, Usui H, Yoshikawa M. Biosci Biotechnol Biochem. 2008 Jan;72(1):257-9. Epub 2008 Jan 7.
Yamada Y, Yamauchi D, Usui H, Zhao H, Yokoo M, Ohinata K, Iwai M, Horiuchi M, Yoshikawa M. Peptides. 2008 Mar;29(3):412-8.
Ohinata K, Fujiwata Y, Shingo F, Masaru I, Masatsugu H, Yoshikawa M. Peptides. 2009 Jun;30(6):1105-8.