NoxA1ds

• Supplier: Tocris Bioscience
• Catalog: 3615
• Prices: $159.00
• Sizes: 1 mg
• Function Type: Inhibitor
• Cas Number: 1435893-78-9
• Formula: C50H88N14O15
• Molecular Weight: 1125.33
• Description: Potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC 50 = 20 nM). Exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. Inhibits NOX1-derived O 2 - production in HT-29 human colon cancer cells. Attenuates VEGF-induced human pulmonary artery endothelial cell migration under hypoxic conditions in vitro . Cell permeable.

Product References

N-(fluorenyl-9-methoxycarbonyl) amino acids, a class of antiinflammatory agents - N-(fluorenyl-9-methoxycarbonyl) amino acids, a class of antiinflammatory agents

Burch RM, Weitzberg M, Blok N, Muhlhauser R, Martin D, Farmer SG, Bator JM, Connor JR, Green M, Ko C, et al.. Proc Natl Acad Sci U S A. 1991 Jan 15;88(2):355-9.

Guinea pig ileitis is attenuated by the leumedin N-(fluorenyl-9- - Guinea pig ileitis is attenuated by the leumedin N-(fluorenyl-9-

Miller MJ, Chotinaruemol S, Sadowska-Krowikca H, Zhang XJ, McIntyre JA, Clark DA. J Pharmacol Exp Ther. 1993 Jul;266(1):468-72.

NPC-15199, a novel anti-inflammatory agent, mobilizes intracellular Ca2+ in - NPC-15199, a novel anti-inflammatory agent, mobilizes intracellular Ca2+ in

Jan CR, Yu CC, Huang JK. Chin J Physiol. 2000 Mar 31;43(1):29-33.