NS 1738

• Supplier: Tocris Bioscience
• Catalog: 3062
• Prices: $139.00, $585.00
• Sizes: 10 mg, 50 mg
• Function Type: Modulator
• Cas Number: 501684-93-1
• Chemical Name: N-(5-Chloro-2-hydroxyphenyl)-N'-[2-chloro-5-(trifluoromethyl)phenyl]urea
• Formula: C14H9Cl2F3N2O2
• Molecular Weight: 365.13
• Purity: >99 %
• Description: Selective positive allosteric modulator of α 7 nicotinic acetylcholine receptors. Exhibits no substantial activity for α 4 β 2, α 3 β 3 and α 1-containing receptors. Displays cognitive-enhancing properties in vivo .

Product References

An allosteric modulator of the alpha7 nicotinic acetylcholine receptor possessing - An allosteric modulator of the alpha7 nicotinic acetylcholine receptor possessing

Timmermann DB, Gronlien JH, Kohlhaas KL, Nielsen EO, Dam E, Jorgensen TD, Ahring PK, Peters D, Holst D, Christensen JK, Malysz J, Briggs CA, Gopalakrishnan M, Olsen GM. J Pharmacol Exp Ther. 2007 Oct;323(1):294-307. Epub 2007 Jul 11.

The antinociceptive effects of nicotinic receptors alpha7-positive allosteric - The antinociceptive effects of nicotinic receptors alpha7-positive allosteric

Freitas K, Carroll FI, Damaj MI. J Pharmacol Exp Ther. 2013 Jan;344(1):264-75.