| Name | NSC 146109 hydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 3034 |
| Prices | $139.00, $585.00 |
| Sizes | 10 mg, 50 mg |
| Cas Number | 59474-01-0 |
| Chemical Name | (10-Methyl-9-anthracenyl)methylcarbamimidothioicacidesterhydrochloride |
| Formula | C17H16N2S.HCl |
| Molecular Weight | 316.85 |
| Purity | >99 % |
| Description | Cell-permeable, genotype-selective antitumor agent that activates p53-dependent transcription. Increases levels of endogenous p53 in tumor cells and protects p53 from Mdm2-mediated degradation. Displays some selectivity for tumor cells vs. normal cells in an MTT cell viability assay. |
| Supplier Page | Shop |
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Berkson RG, Hollick JJ, Westwood NJ, Woods JA, Lane DP, Lain S. Int J Cancer. 2005 Jul 10;115(5):701-10.