| Name | NSC 319726 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 2161 |
| Prices | $175.00, $709.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Activator |
| Cas Number | 71555-25-4 |
| Chemical Name | 1-Azetidinecarbothioicacid[1-(2-pyridinyl)ethylidene]hydrazide |
| Formula | C11H14N4S |
| Molecular Weight | 234.32 |
| Purity | >98 % |
| Description | Reactivator of mutant p53. Restores wild type p53 structure and function to the p53 R175 mutant. Inhibits growth of fibroblasts expressing the p53 R175 mutation (IC 50 = 8 nM). Also inhibits growth of xenograft tumors expressing the p53 R175 mutation in vivo . |
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