| Name | NSC 405020 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 2521 |
| Prices | $109.00, $459.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 7497-07-6 |
| Chemical Name | 3,4-Dichloro-N-(1-methylbutyl)benzamide |
| Formula | C12H15Cl2NO |
| Molecular Weight | 260.16 |
| Purity | >99 % |
| Description | Membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor (IC 50 > 100 μ mol/L). Directly interacts with the hemopexin domain (PEX) of MT1-MMP, affecting homodimerization and repressing its pro-tumorigenic activity in vivo . Displays no effect on the catalytic activity of MT1-MMP or MMP-2. |
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