Name | NTNCB hydrochloride |
---|---|
Supplier | Tocris Bioscience |
Catalog | 1547 |
Prices | $199.00, $825.00 |
Sizes | 10 mg, 50 mg |
Function Type | Antagonist |
Cas Number | 191931-56-3 |
Chemical Name | 2-Nitro-N-[[trans-4-[[[(1,2,3,4-tetrahydro-2-naphthalenyl)methyl]amino]methyl]cyclohexyl]methyl]benzenesulfonamidehydrochloride |
Formula | C25H33N3O4S.HCl |
Molecular Weight | 508.07 |
Purity | >98 % |
Description | Selective, non-peptide competitive NPY Y 5 antagonist. K i values are 8.0 and 16032 nM at human recombinant Y 5 and Y 1 receptors respectively. Potently antagonizes NPY inhibition of forskolin-stimulated cAMP. Displays some affinity for cloned human D 2 and α 2C receptors (K i values are 63 and 100 nM respectively). |
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