| Name | NU 6140 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 3135 |
| Prices | $199.00, $825.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 444723-13-1 |
| Chemical Name | 4-[[6-(Cyclohexylmethoxy)-1H-purin-2-yl]amino]-N,N-diethylbenzamide |
| Formula | C23H30N6O2 |
| Molecular Weight | 422.52 |
| Purity | >99 % |
| Description | Cyclin-dependent kinase 2 (cdk2) inhibitor; induces cell-cycle arrest at the G 2 -M phase. 10- to 36-fold more selective for cdk2-cyclin A over other cdks (IC 50 = 0.41 μ M for cdk2-cyclin A). Potentiates the apoptotic effect of taxol (Cat. No. 1097) in HeLa cells; down-regulates the antiapoptotic protein survivin. |
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