NVP 231

• Supplier: Tocris Bioscience
• Catalog: 3984
• Prices: $169.00, $705.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 362003-83-6
• Chemical Name: N-[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3.3.1.13,7]decane-1-carboxamide
• Formula: C25H25N3O2S
• Molecular Weight: 431.55
• Purity: >98 %
• Description: Potent, selective and reversible ceramide kinase (CerK) inhibitor (IC 50 = 12 nM in vitro ). Displays selectivity for CerK over sphingosine kinases (IC 50 ≥100 μ M) and other lipid kinases.

Product References

A secondary assay for ceramide kinase inhibitors based on cell growth inhibition - A secondary assay for ceramide kinase inhibitors based on cell growth inhibition

Graf C, Rovina P, Bornancin F. Anal Biochem. 2009 Jan 1;384(1):166-9.

Ceramide kinase deficiency impairs microendothelial cell angiogenesis in vitro. - Ceramide kinase deficiency impairs microendothelial cell angiogenesis in vitro.

Niwa S, Graf C, Bornancin F. Microvasc Res. 2009 May;77(3):389-93.