NXY 059

• Supplier: Tocris Bioscience
• Catalog: 2067
• Prices: $129.00, $535.00
• Sizes: 10 mg, 50 mg
• Cas Number: 168021-79-2
• Chemical Name: 4-[[(1,1-Dimethylethyl)oxoimino]methyl]-1,3-benzenedisulfonicaciddisodiumsalt
• Formula: C11H13NNa2O7S2
• Molecular Weight: 381.33
• Purity: >98 %
• Description: Free radical trapping agent. Reduces infarct size and preserves brain function in several animal models of acute ischemic stroke. Neuroprotectant.

Product References

Efficacy of disodium 4-[(tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide - Efficacy of disodium 4-[(tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide

Peeling J, Del Bigio MR, Corbett D, Green AR, Jackson DM. Neuropharmacology. 2001 Mar;40(3):433-9.

Effect of NXY-059 on infarct volume after transient or permanent middle cerebral - Effect of NXY-059 on infarct volume after transient or permanent middle cerebral

Sydserff SG, Borelli AR, Green AR, Cross AJ. Br J Pharmacol. 2002 Jan;135(1):103-12.

Cerebrovascular protection as a possible mechanism for the protective effects of - Cerebrovascular protection as a possible mechanism for the protective effects of

Culot M, Mysiorek C, Renftel M, Roussel BD, Hommet Y, Vivien D, Cecchelli R, Fenart L, Berezowski V, Dehouck MP, Lundquist S. Brain Res. 2009 Oct 19;1294:144-52.