| Name | O-2093 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 1655 |
| Prices | $139.00, $585.00 |
| Sizes | 5 mg, 25 mg |
| Function Type | Inhibitor |
| Cas Number | 439080-01-0 |
| Chemical Name | N-(bis-3-chloro-4-hydroxybenzyl)-5Z,8Z,11Z,14Z-eicosatetraenamide |
| Formula | C34H43Cl2NO3 |
| Molecular Weight | 584.62 |
| Description | Inhibitor of anandamide uptake (IC 50 = 17.3 μ M) with little or no activity at CB 1 , CB 2 , TRPV1 and FAAH. Intravenous administration inhibits limb spasticity in mice with chronic relapsing experimental allergic encephalomyelitis (CREAE). |
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Di Marzo V, Griffin G, De Petrocellis L, Brandi I, Bisogno T, Williams W, Grier MC, Kulasegram S, Mahadevan A, Razdan RK, Martin BR. J Pharmacol Exp Ther. 2002 Mar;300(3):984-91.
Ligresti A, Cascio MG, Pryce G, Kulasegram S, Beletskaya I, De Petrocellis L, Saha B, Mahadevan A, Visintin C, Wiley JL, Baker D, Martin BR, Razdan RK, Di Marzo V. Br J Pharmacol. 2006 Jan;147(1):83-91.