| Name | Olanzapine |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 1136 |
| Prices | $69.00, $279.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 132539-06-1 |
| Chemical Name | 2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine |
| Formula | C17H20N4S |
| Molecular Weight | 312.43 |
| Purity | >99 % |
| Description | Antagonist of 5-HT 2A and dopamine D 2 receptors (K i values are 4 and 11 nM respectively). Also displays affinity for a range of other receptors including D 1 and D 4 , 5-HT 2C , α 1 , H 1 and M 1-4 receptors (K i values range between 1.9 and 31 nM) . Atypical antipsychotic. Displays anticholinergic properties. |
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Moore NA, Tye NC, Axton MS, Risius FC. J Pharmacol Exp Ther. 1992 Aug;262(2):545-51.
Bymaster FP, Calligaro DO, Falcone JF, Marsh RD, Moore NA, Tye NC, Seeman P, Wong DT. Neuropsychopharmacology. 1996 Feb;14(2):87-96.