Oleamide

• Supplier: Tocris Bioscience
• Catalog: 1641
• Prices: $69.00, $259.00
• Sizes: 10 mg, 50 mg
• Cas Number: 301-02-0
• Chemical Name: cis-9-Octadecenamide
• Formula: C18H35NO
• Molecular Weight: 281.48
• Purity: >98 %
• Description: Endogenous sleep-inducing lipid. Acts as an agonist at the CB 1 cannabinoid receptor (EC 50 = 1.64 μ M). Also appears to potentiate the actions of 5-HT on 5-HT 2A and 2C receptors, and act via an allosteric regulatory site on 5-HT 7 receptors.

Product References

Chemical characterization of a family of brain lipids that induce sleep. - Chemical characterization of a family of brain lipids that induce sleep.

Cravatt BF, Prospero-Garcia O, Siuzdak G, Gilula NB, Henriksen SJ, Boger DL, Lerner RA. Science. 1995 Jun 9;268(5216):1506-9.

Brain lipids that induce sleep are novel modulators of 5-hydroxytrypamine - Brain lipids that induce sleep are novel modulators of 5-hydroxytrypamine

Huidobro-Toro JP, Harris RA. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):8078-82.

Allosteric regulation by oleamide of the binding properties of - Allosteric regulation by oleamide of the binding properties of

Hedlund PB, Carson MJ, Sutcliffe JG, Thomas EA. Biochem Pharmacol. 1999 Dec 1;58(11):1807-13.

Oleamide is a selective endogenous agonist of rat and human CB1 cannabinoid - Oleamide is a selective endogenous agonist of rat and human CB1 cannabinoid

Leggett JD, Aspley S, Beckett SR, D'Antona AM, Kendall DA, Kendall DA. Br J Pharmacol. 2004 Jan;141(2):253-62. Epub 2004 Jan 5.