PACAP 6-38

Name PACAP 6-38
Supplier Tocris Bioscience
Catalog 1186
Prices $149.00
Sizes 100 µg
Function Type Antagonist
Cas Number 143748-18-9
Formula C182H300N56O45S
Molecular Weight 4024.78
Description Potent and competitive pituitary adenylate cyclase-activating polypeptide receptor (PAC) 1 antagonist (IC 50 = 2 nM). Inhibits PACAP(1-27)-induced stimulation of adenylate cyclase (K i = 1.5 nM). Antitumor activity in vivo .
Supplier Page Shop

Product References

Structural requirements for the occupancy of pituitary - Structural requirements for the occupancy of pituitary

Robberecht P, Gourlet P, De Neef P, Woussen-Colle MC, Vandermeers-Piret MC, Vandermeers A, Christophe J. Eur J Biochem. 1992 Jul 1;207(1):239-46.

PACAP(6-38) inhibits the growth of prostate cancer cells. - PACAP(6-38) inhibits the growth of prostate cancer cells.

Leyton J, Coelho T, Coy DH, Jakowlew S, Birrer MJ, Moody TW. Cancer Lett. 1998 Mar 13;125(1-2):131-9.

The neuropeptide PACAP promotes the alpha-secretase pathway for processing the - The neuropeptide PACAP promotes the alpha-secretase pathway for processing the

Kojro E, Postina R, Buro C, Meiringer C, Gehrig-Burger K, Fahrenholz F. FASEB J. 2006 Mar;20(3):512-4. Epub 2006 Jan 9.