Name | PALDA |
---|---|
Supplier | Tocris Bioscience |
Catalog | 2940 |
Prices | $105.00 |
Sizes | 10 mg |
Cas Number | 136181-87-8 |
Chemical Name | N-[2-(3,4-Dihydroxyphenyl)ethyl]hexadecanamide |
Formula | C24H41NO3 |
Molecular Weight | 391.59 |
Purity | >98 % |
Description | Endogenous fatty acid dopamide that displays 'entourage' effects on endovanilloids NADA and anandamide. Inactive at TRPV1 and CB 1 receptors (at concentrations up to 5 μ M) and does not inhibit AMT or FAAH (IC 50 > 25 μ M). However, potentiates TRPV1-mediated effects of NADA; lowers EC 50 from ~ 90 to ~ 30 nM. |
Supplier Page | Shop |
Chu CJ, Huang SM, De Petrocellis L, Bisogno T, Ewing SA, Miller JD, Zipkin RE, Daddario N, Appendino G, Di Marzo V, Walker JM. J Biol Chem. 2003 Apr 18;278(16):13633-9. Epub 2003 Feb 4.
De Petrocellis L, Chu CJ, Moriello AS, Kellner JC, Walker JM, Di Marzo V. Br J Pharmacol. 2004 Sep;143(2):251-6. Epub 2004 Aug 2.