[cPP 1-7 ,NPY 19-23 ,Ala 31 ,Aib 32 ,Gln 34 ] - hPancreatic Polypeptide

Name [cPP 1-7 ,NPY 19-23 ,Ala 31 ,Aib 32 ,Gln 34 ] - hPancreatic Polypeptide
Supplier Tocris Bioscience
Catalog 1154
Prices $439.00
Sizes 1 mg
Function Type Agonist
Cas Number 313988-89-5
Formula C183H281N57O54S2
Molecular Weight 4207.67
Description Potent, selective peptide agonist for the neuropeptide Y Y 5 receptor (IC 50 values for inhibition of NPY binding to human Y 5 , Y 1 , Y 2 and Y 4 receptors are 0.24, 530, > 500, and 51 nM respectively, K i at Y 5 = 0.1 - 0.15 nM). Stimulates food intake in vivo .
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Product References

The first selective agonist for the neuropeptide YY5 receptor increases food - The first selective agonist for the neuropeptide YY5 receptor increases food

Cabrele C, Langer M, Bader R, Wieland HA, Doods HN, Zerbe O, Beck-Sickinger AG. J Biol Chem. 2000 Nov 17;275(46):36043-8.

BODIPY-conjugated neuropeptide Y ligands: new fluorescent tools to tag Y1, Y2, Y4 - BODIPY-conjugated neuropeptide Y ligands: new fluorescent tools to tag Y1, Y2, Y4

Dumont Y, Gaudreau P, Mazzuferi M, Langlois D, Chabot JG, Fournier A, Simonato M, Quirion R. Br J Pharmacol. 2005 Dec;146(8):1069-81.